News https://bmcdb.ucdavis.edu/news News for BMCDB Graduate Group en Gatekeeper of the Cellular Highway: Study Reveals Novel Behaviors of the Alzheimer’s Disease Protein Tau https://bmcdb.ucdavis.edu/news/gatekeeper-cellular-highway-study-reveals-novel-behaviors-alzheimers-disease-protein-tau <span class="field field--name-title field--type-string field--label-hidden">Gatekeeper of the Cellular Highway: Study Reveals Novel Behaviors of the Alzheimer’s Disease Protein Tau</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/4371" typeof="schema:Person" property="schema:name" datatype="">Kelli Smith</span> </span> <span class="field field--name-created field--type-created field--label-hidden">September 04, 2019</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/Tau-Tangles-College-of-Biological-Sciences-UC-Davis_Page_1.jpg?h=c673cd1c&amp;itok=LEaV2I-W" width="1280" height="720" alt="In a new study appearing in Nature Cell Biology, UC Davis researchers found that tau molecules can congregate together in a novel, reversible way, which appears to be distinct from the irreversible tangle formation observed in neurodegenerative disease. N Molecular Systems, Inc." title="In a new study appearing in Nature Cell Biology, UC Davis researchers found that tau molecules can congregate together in a novel, reversible way, which appears to be distinct from the irreversible tangle formation observed in neurodegenerative disease. N Molecular Systems, Inc." typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="In the brains of those with Alzheimer’s disease, traumatic brain injury and other neurodegenerative disorders, insoluble fibers composed of a protein called tau build up inside of neurons, eventually creating a tangled mess characteristic of these diseases. "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "In the brains of those with Alzheimer’s disease, traumatic brain injury and other neurodegenerative disorders, insoluble fibers composed of a protein called tau build up inside of neurons, eventually creating a tangled mess characteristic of these diseases. " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>In the brains of those with Alzheimer’s disease, traumatic brain injury and other neurodegenerative disorders, insoluble fibers composed of a protein called tau build up inside of neurons, eventually creating a tangled mess characteristic of these diseases.</p> <p> </p> <p><a class="btn--primary" href="https://biology.ucdavis.edu/news/gatekeeper-cellular-highway-study-reveals-novel-behaviors-alzheimers-disease-protein-tau">Read the Complete Story  </a></p> </div> Wed, 04 Sep 2019 16:00:28 +0000 Kelli Smith 191 at https://bmcdb.ucdavis.edu Mitochondrial Chitter-Chatter: Unveiling the Molecular Structures of Cellular Respiration https://bmcdb.ucdavis.edu/news/mitochondrial-chitter-chatter-unveiling-molecular-structures-cellular-respiration <span class="field field--name-title field--type-string field--label-hidden">Mitochondrial Chitter-Chatter: Unveiling the Molecular Structures of Cellular Respiration </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/4371" typeof="schema:Person" property="schema:name" datatype="">Kelli Smith</span> </span> <span class="field field--name-created field--type-created field--label-hidden">September 03, 2019</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/James-Letts-College-of-Biological-Sciences-UC-Davis-3.jpg?h=c673cd1c&amp;itok=7g5xuGd6" width="1280" height="720" alt="In a Molecular Cell study, Assistant Professor James Letts and colleagues revealed that the function between the complexes in the respiratory supercomplex is more nuanced and variable than previously hypothesized. David Slipher/UC Davis " title="In a Molecular Cell study, Assistant Professor James Letts and colleagues revealed that the function between the complexes in the respiratory supercomplex is more nuanced and variable than previously hypothesized. David Slipher/UC Davis " typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="In order to generate energy, our bodies transfer electrons from food—sugars, fats and proteins—to molecular oxygen, which allows our cells to respire and function. Performed by the mitochondrial electron transport chain (ETC), this process creates energy-storing and -transporting adenosine triphosphate (ATP), the “molecular currency” for energy in the cell. "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "In order to generate energy, our bodies transfer electrons from food—sugars, fats and proteins—to molecular oxygen, which allows our cells to respire and function. Performed by the mitochondrial electron transport chain (ETC), this process creates energy-storing and -transporting adenosine triphosphate (ATP), the “molecular currency” for energy in the cell. " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>In order to generate energy, our bodies transfer electrons from food—sugars, fats and proteins—to molecular oxygen, which allows our cells to respire and function. Performed by the mitochondrial electron transport chain (ETC), this process creates energy-storing and -transporting adenosine triphosphate (ATP), the “molecular currency” for energy in the cell.</p> <p> </p> <p><a class="btn--lg btn--primary" href="https://biology.ucdavis.edu/news/mitochondrial-chitter-chatter-unveiling-molecular-structures-cellular-respiration">Read the Complete Story  </a></p> </div> Tue, 03 Sep 2019 19:02:57 +0000 Kelli Smith 186 at https://bmcdb.ucdavis.edu The Repellence Cocktail: Mosquito Sense of Smell Reveals More Mysteries https://bmcdb.ucdavis.edu/news/repellence-cocktail-mosquito-sense-smell-reveals-more-mysteries <span class="field field--name-title field--type-string field--label-hidden">The Repellence Cocktail: Mosquito Sense of Smell Reveals More Mysteries</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/4371" typeof="schema:Person" property="schema:name" datatype="">Kelli Smith</span> </span> <span class="field field--name-created field--type-created field--label-hidden">August 02, 2019</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/Walter-Leal-Lab-College-of-Biological-Sciences-4.jpg?h=c673cd1c&amp;itok=9xW9efLv" width="1280" height="720" alt="In a study published in iScience, Distinguished Professor Walter Leal and his colleagues showed that the southern house mosquito possesses a single odorant receptor that exhibits both inhibitory and excitatory responses. David Slipher/UC Davis" title="In a study published in iScience, Distinguished Professor Walter Leal and his colleagues showed that the southern house mosquito possesses a single odorant receptor that exhibits both inhibitory and excitatory responses. David Slipher/UC Davis" typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="When nibbling mosquitoes cause irritation, the sensible move is to grab mosquito repellent. Distinguished Professor Walter Leal, Department of Molecular and Cellular Biology, likes to remind his students of this. But if they’re stepping outside for only a short period of time during the buggy Davis summers, Leal will offer a natural repellent like methyl salicylate, otherwise known as wintergreen oil. "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "When nibbling mosquitoes cause irritation, the sensible move is to grab mosquito repellent. Distinguished Professor Walter Leal, Department of Molecular and Cellular Biology, likes to remind his students of this. But if they’re stepping outside for only a short period of time during the buggy Davis summers, Leal will offer a natural repellent like methyl salicylate, otherwise known as wintergreen oil. " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>When nibbling mosquitoes cause irritation, the sensible move is to grab mosquito repellent. Distinguished Professor Walter Leal, Department of Molecular and Cellular Biology, likes to remind his students of this. But if they’re stepping outside for only a short period of time during the buggy Davis summers, Leal will offer a natural repellent like methyl salicylate, otherwise known as wintergreen oil.</p> <p> </p> <p><a class="btn--primary" href="https://biology.ucdavis.edu/news/repellence-cocktail-mosquito-sense-smell-reveals-more-mysteries">Read the Complete Story</a></p> </div> Fri, 02 Aug 2019 15:31:45 +0000 Kelli Smith 181 at https://bmcdb.ucdavis.edu Mapping Cells in the “Immortal” Regenerating Hydra https://bmcdb.ucdavis.edu/news/mapping-cells-immortal-regenerating-hydra <span class="field field--name-title field--type-string field--label-hidden">Mapping Cells in the “Immortal” Regenerating Hydra</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/4371" typeof="schema:Person" property="schema:name" datatype="">Kelli Smith</span> </span> <span class="field field--name-created field--type-created field--label-hidden">July 25, 2019</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/Juliano-Lab-College-of-Biological-Sciences-UC-Davis-1.jpg?h=c673cd1c&amp;itok=T-8hpB1g" width="1280" height="720" alt="Hydra boast stem cells that exist in a continuous state of renewal and seem to hold within their genomic code the key to biological immortality. Stefan Siebert" title="Hydra boast stem cells that exist in a continuous state of renewal and seem to hold within their genomic code the key to biological immortality. Stefan Siebert" typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="Unlike the stem cells of an adult human, the stem cells of an adult Hydra—a small freshwater invertebrate related to jellyfish and corals—are in a constant state of renewal, bestowing it with amazing regenerative capabilities and nearly biological immortality. Around 100,000 cells make up the Hydra body, and amazingly, these cells renew every 20 days thanks to the Hydra’s bottomless well of stem cells. "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "Unlike the stem cells of an adult human, the stem cells of an adult Hydra—a small freshwater invertebrate related to jellyfish and corals—are in a constant state of renewal, bestowing it with amazing regenerative capabilities and nearly biological immortality. Around 100,000 cells make up the Hydra body, and amazingly, these cells renew every 20 days thanks to the Hydra’s bottomless well of stem cells. " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Unlike the stem cells of an adult human, the stem cells of an adult Hydra—a small freshwater invertebrate related to jellyfish and corals—are in a constant state of renewal, bestowing it with amazing regenerative capabilities and nearly biological immortality. Around 100,000 cells make up the Hydra body, and amazingly, these cells renew every 20 days thanks to the Hydra’s bottomless well of stem cells.</p> <p> </p> <p><a class="btn--primary" href="https://biology.ucdavis.edu/news/mapping-cells-immortal-regenerating-hydra">Read the Complete Story</a></p> <p> </p> </div> Thu, 25 Jul 2019 21:45:07 +0000 Kelli Smith 176 at https://bmcdb.ucdavis.edu The Plant-Pathogen Arms Race: Nature Communications Study Reveals Key Player in Plant Immunity https://bmcdb.ucdavis.edu/news/plant-pathogen-arms-race-nature-communications-study-reveals-key-player-plant-immunity <span class="field field--name-title field--type-string field--label-hidden">The Plant-Pathogen Arms Race: Nature Communications Study Reveals Key Player in Plant Immunity</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/4371" typeof="schema:Person" property="schema:name" datatype="">Kelli Smith</span> </span> <span class="field field--name-created field--type-created field--label-hidden">July 22, 2019</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/Tobacco-mosaic-virus-symptoms-orchid-UC-Davis-College-of-Biological-Sciences.jpg?h=c673cd1c&amp;itok=4PepQ9tM" width="1280" height="720" alt="Orchid leaves with symptoms of tobacco mosaic virus. Department of Plant Pathology, North Carolina State University, Bugwood.org" title="Orchid leaves with symptoms of tobacco mosaic virus. Department of Plant Pathology, North Carolina State University, Bugwood.org" typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="The co-evolutionary arms race between plants and pathogens is one of biological balance. Plants want to defend themselves from invaders, while pathogens want to infect their hosts without killing them to propagate. Plant biologists are keen to understand the molecular battles occurring in infected plant cell territory. "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "The co-evolutionary arms race between plants and pathogens is one of biological balance. Plants want to defend themselves from invaders, while pathogens want to infect their hosts without killing them to propagate. Plant biologists are keen to understand the molecular battles occurring in infected plant cell territory. " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The co-evolutionary arms race between plants and pathogens is one of biological balance. Plants want to defend themselves from invaders, while pathogens want to infect their hosts without killing them to propagate. Plant biologists are keen to understand the molecular battles occurring in infected plant cell territory.</p> <p> </p> <p><a class="btn--primary" href="https://biology.ucdavis.edu/news/plant-pathogen-arms-race-nature-communications-study-reveals-key-player-plant-immunity">Read the Complete Story</a></p> </div> Mon, 22 Jul 2019 19:58:34 +0000 Kelli Smith 171 at https://bmcdb.ucdavis.edu Discovering Curiosity: Tilling the Fields of Plant Molecular Biology with Professor Savithramma Dinesh-Kumar https://bmcdb.ucdavis.edu/news/discovering-curiosity-tilling-fields-plant-molecular-biology-professor-savithramma-dinesh <span class="field field--name-title field--type-string field--label-hidden">Discovering Curiosity: Tilling the Fields of Plant Molecular Biology with Professor Savithramma Dinesh-Kumar</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/4371" typeof="schema:Person" property="schema:name" datatype="">Kelli Smith</span> </span> <span class="field field--name-created field--type-created field--label-hidden">July 16, 2019</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/Savithramma-Dinesh-Kumar-College-of-Biological-Sciences-UC-Davis-2.jpg?h=c673cd1c&amp;itok=FyE0w9Z5" width="1280" height="720" alt="For his excellence in molecular plant pathology research, Professor Savithramma Dinesh-Kumar recently received the Noel T. Keen Award from The American Phytopathological Society. David Slipher/UC Davis" title="For his excellence in molecular plant pathology research, Professor Savithramma Dinesh-Kumar recently received the Noel T. Keen Award from The American Phytopathological Society. David Slipher/UC Davis" typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="For his excellence in research, Dinesh-Kumar has received the American Phytopathological Society&#039;s Noel T. Keen Award  His interest in plants goes back to his youth working with his father on his family&#039;s farm in India His well-published research focuses on host-microbe interactions and plant defense tactics "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "For his excellence in research, Dinesh-Kumar has received the American Phytopathological Society&#039;s Noel T. Keen Award  His interest in plants goes back to his youth working with his father on his family&#039;s farm in India His well-published research focuses on host-microbe interactions and plant defense tactics " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p><em>For his excellence in research, Dinesh-Kumar has received the American Phytopathological Society's Noel T. Keen Award </em></p> <p><em>His interest in plants goes back to his youth working with his father on his family's farm in India</em></p> <p><em>His well-published research focuses on host-microbe interactions and plant defense tactics</em></p> <p> </p> <p><a class="btn--primary" href="https://biology.ucdavis.edu/news/discovering-curiosity-tilling-fields-plant-molecular-biology-savithramma-dinesh-kumar">Read the Complete Story</a></p> </div> Tue, 16 Jul 2019 18:21:42 +0000 Kelli Smith 166 at https://bmcdb.ucdavis.edu Two BMCDB Students Receive National Science Foundation Graduate Research Fellowship https://bmcdb.ucdavis.edu/news/two-bmcdb-students-receive-national-science-foundation-graduate-research-fellowship <span class="field field--name-title field--type-string field--label-hidden">Two BMCDB Students Receive National Science Foundation Graduate Research Fellowship</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/4371" typeof="schema:Person" property="schema:name" datatype="">Kelli Smith</span> </span> <span class="field field--name-created field--type-created field--label-hidden">April 09, 2019</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/NSF_logo_0.png?h=157bdb64&amp;itok=INiQMHSv" width="1280" height="720" alt="National Science Foundation Logo" title="National Science Foundation" typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="Congratulations to Jamie Ho, current BMCDB second year student, and Yesica Mercado-Ayon, UCD PREP Scholar and incoming BMCDB student, on being selected for the 2019 NSF GRFP Fellowships! "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "Congratulations to Jamie Ho, current BMCDB second year student, and Yesica Mercado-Ayon, UCD PREP Scholar and incoming BMCDB student, on being selected for the 2019 NSF GRFP Fellowships! " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p><span><span><span>Congratulations to Jamie Ho, current BMCDB second year student, and Yesica Mercado-Ayon, UCD PREP Scholar and incoming BMCDB student, on being selected for the 2019 NSF GRFP Fellowships! </span></span></span></p> </div> <div class="field field--name-field-sf-tags field--type-entity-reference field--label-above"> <div class="field__label">Tags</div> <div class="field__items"> <div class="field__item"><a href="/tags/awards-and-recognition" hreflang="en">Awards and Recognition</a></div> </div> </div> Tue, 09 Apr 2019 22:17:01 +0000 Kelli Smith 151 at https://bmcdb.ucdavis.edu Discovering Curiosity: Building Mini-Organs to Fight Pancreatic Cancer with New Faculty Chang-il Hwang https://bmcdb.ucdavis.edu/news/discovering-curiosity-building-mini-organs-fight-pancreatic-cancer-new-faculty-chang-il-hwang <span class="field field--name-title field--type-string field--label-hidden">Discovering Curiosity: Building Mini-Organs to Fight Pancreatic Cancer with New Faculty Chang-il Hwang</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/4371" typeof="schema:Person" property="schema:name" datatype="">Kelli Smith</span> </span> <span class="field field--name-created field--type-created field--label-hidden">March 21, 2019</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/Chang-Il-Hwang-College-of-Biological-Sciences-UC-Davis-2.jpg?h=c673cd1c&amp;itok=GsIW3Wv_" width="1280" height="720" alt="On the hunt for methods to aid early detection and better therapeutic treatments, Assistant Professor Chang-il Hwang developed pancreatic cancer organoids, miniature organ models that allow him to study pancreatic cancer from its earliest stages. David Slipher/UC Davis" title="On the hunt for methods to aid early detection and better therapeutic treatments, Assistant Professor Chang-il Hwang developed pancreatic cancer organoids, miniature organ models that allow him to study pancreatic cancer from its earliest stages. David Slipher/UC Davis" typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="When a healthy cell turns cancerous a cascade of events enables the cancer to spread throughout the body. But its origin lies within a single progenitor cell. “What goes wrong with that particular cell?” asked Assistant Professor Chang-il Hwang, Department of Microbiology and Molecular Genetics. “Something happens at the molecular level. One DNA molecule, or one protein molecule changes.”  "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "When a healthy cell turns cancerous a cascade of events enables the cancer to spread throughout the body. But its origin lies within a single progenitor cell. “What goes wrong with that particular cell?” asked Assistant Professor Chang-il Hwang, Department of Microbiology and Molecular Genetics. “Something happens at the molecular level. One DNA molecule, or one protein molecule changes.”  " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>When a healthy cell turns cancerous a cascade of events enables the cancer to spread throughout the body. But its origin lies within a single progenitor cell.</p> <p>“What goes wrong with that particular cell?” asked Assistant Professor Chang-il Hwang, Department of Microbiology and Molecular Genetics. “Something happens at the molecular level. One DNA molecule, or one protein molecule changes.”</p> <p> </p> <p><a class="btn--primary" href="https://biology.ucdavis.edu/news/discovering-curiosity-building-mini-organs-fight-pancreatic-cancer-new-faculty-chang-il-hwang">Read the Complete Story</a></p> </div> <div class="field field--name-field-sf-article-category field--type-entity-reference field--label-above"> <div class="field__label">Category</div> <div class="field__item"><a href="/articles/human-animal-health" hreflang="en">Human &amp; Animal Health</a></div> </div> Thu, 21 Mar 2019 20:41:43 +0000 Kelli Smith 146 at https://bmcdb.ucdavis.edu Sex-swapping Zebrafish Hold Clues for Reproductive Development Diseases in Humans https://bmcdb.ucdavis.edu/news/sex-swapping-zebrafish-hold-clues-reproductive-development-diseases-humans <span class="field field--name-title field--type-string field--label-hidden">Sex-swapping Zebrafish Hold Clues for Reproductive Development Diseases in Humans</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/1996" typeof="schema:Person" property="schema:name" datatype="">Greg Watry</span> </span> <span class="field field--name-created field--type-created field--label-hidden">January 23, 2019</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/Zebrafish-College-of-Biological-Sciences-UC-Davis.jpg?h=5e27a39a&amp;itok=ymTUDOcN" width="1280" height="720" alt="zebrafish swim in a tank " typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="In a study appearing in Genetics, BMCDB Graduate Group faculty chair Bruce Draper and UC Davis researchers relay new discoveries about the molecular mechanisms behind sexual determination. Using zebrafish, they highlighted the gene responsible for determining whether the fish will develop into a female or a male. "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "In a study appearing in Genetics, BMCDB Graduate Group faculty chair Bruce Draper and UC Davis researchers relay new discoveries about the molecular mechanisms behind sexual determination. Using zebrafish, they highlighted the gene responsible for determining whether the fish will develop into a female or a male. " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>In a study appearing in Genetics, BMCDB Graduate Group faculty chair Bruce Draper and UC Davis researchers relay new discoveries about the molecular mechanisms behind sexual determination. Using zebrafish, they highlighted the gene responsible for determining whether the fish will develop into a female or a male.</p> <p><a class="btn--primary" href="https://biology.ucdavis.edu/news/sex-swapping-zebrafish-hold-clues-reproductive-development-diseases-humans">Read the complete story</a></p> </div> <div class="field field--name-field-sf-article-category field--type-entity-reference field--label-above"> <div class="field__label">Category</div> <div class="field__item"><a href="/articles/human-animal-health" hreflang="en">Human &amp; Animal Health</a></div> </div> Wed, 23 Jan 2019 22:10:25 +0000 Greg Watry 141 at https://bmcdb.ucdavis.edu Diabetes Research in Huising Lab Emphasizes Importance of Reproducibility in Science https://bmcdb.ucdavis.edu/news/diabetes-research-huising-lab-emphasizes-importance-reproducibility-science <span class="field field--name-title field--type-string field--label-hidden">Diabetes Research in Huising Lab Emphasizes Importance of Reproducibility in Science</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/16" typeof="schema:Person" property="schema:name" datatype="">David Slipher</span> </span> <span class="field field--name-created field--type-created field--label-hidden">June 21, 2018</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/Sharon-Lee-Mark-Huising-College-of-Biological-Sciences-UC-Davis.jpg?h=c673cd1c&amp;itok=G2Sd7q1z" width="1280" height="720" alt="Sharon Lee and Mark Huising in lab" title="Sharon Lee, a Biochemistry, Molecular, Cellular and Developmental Biology graduate student, and Mark Huising, associate professor of neurobiology, physiology and behavior, study the cellular mechanisms of diabetes. David Slipher/UC Davis" typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="In a paper appearing in Cell Metabolism, Associate Professor Mark Huising, Department of Neurobiology, Physiology and Behavior, and Biochemistry, Molecular, Cellular and Developmental Biology graduate student Sharon Lee refute a previous study that claimed an antimalarial drug could be used to treat type 1 diabetes. "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "In a paper appearing in Cell Metabolism, Associate Professor Mark Huising, Department of Neurobiology, Physiology and Behavior, and Biochemistry, Molecular, Cellular and Developmental Biology graduate student Sharon Lee refute a previous study that claimed an antimalarial drug could be used to treat type 1 diabetes. " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>In the United States, around 30 million people live with diabetes. It’s among the top 10 leading causes of death in the country, according to the Centers for Disease Control and Prevention. With no cure, treatment and control remain the only options for diabetes patients.</p> <p>In a paper appearing in <a href="http://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)30614-9%20"><em>Cell Metabolism</em></a><em>,</em> College of Biological Sciences Associate Professor Mark Huising, Department of Neurobiology, Physiology and Behavior, and Biochemistry, Molecular, Cellular and Developmental Biology graduate student Sharon Lee refute a previous study that claimed an antimalarial drug could be used to treat type 1 diabetes.</p> <p><a class="btn--primary" href="https://biology.ucdavis.edu/news/diabetes-research-huising-lab-emphasizes-importance-reproducibility-science">Read the full story to learn more about Huising's and Lee's diabetes research</a></p> </div> <div class="field field--name-field-sf-article-category field--type-entity-reference field--label-above"> <div class="field__label">Category</div> <div class="field__item"><a href="/articles/human-animal-health" hreflang="en">Human &amp; Animal Health</a></div> </div> Thu, 21 Jun 2018 15:27:28 +0000 David Slipher 111 at https://bmcdb.ucdavis.edu Connecting the Molecular Dots of Heart Disease https://bmcdb.ucdavis.edu/news/connecting-molecular-dots-heart-disease <span class="field field--name-title field--type-string field--label-hidden">Connecting the Molecular Dots of Heart Disease</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/16" typeof="schema:Person" property="schema:name" datatype="">David Slipher</span> </span> <span class="field field--name-created field--type-created field--label-hidden">May 14, 2018</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/aldrin-gomes.jpg?h=c673cd1c&amp;itok=K_izStmA" width="1280" height="720" alt="Aldrin Gomes" title="Associate Professor Aldrin Gomes, Department of Neurobiology, Physiology and Behavior, studies the molecular origins of heart disease." typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="Associate Professor Aldrin Gomes, Department of Neurobiology, Physiology and Behavior, studies the underpinnings of heart disease. He’s searching for molecular clues that will help medical professionals better manage heart disease. "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "Associate Professor Aldrin Gomes, Department of Neurobiology, Physiology and Behavior, studies the underpinnings of heart disease. He’s searching for molecular clues that will help medical professionals better manage heart disease. " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The most common genetic heart disease is also a silent one. Hypertrophic cardiomyopathy (HCM) affects one in 500 adults, and with few symptoms, it usually goes unnoticed. According to the American Heart Association, the disease is a common cause of sudden cardiac arrest among young adults.</p> <p>Associate Professor Aldrin Gomes, Department of Neurobiology, Physiology and Behavior in the College of Biological Sciences at UC Davis, studies the underpinnings of heart disease, focusing on the machinery within heart cells responsible for producing the heartbeat. Along with colleagues in the Gomes Lab, he’s searching for molecular clues that will help medical professionals better manage heart disease.</p> <p>“Heart disease is still the number one killer around the world,” said Gomes, who holds a joint appointment with the UC Davis Health Department of Physiology and Membrane Biology. “How can we reduce the number of people that die from heart disease? A lot of us have family members with some heart disease.” </p> <p><a class="btn--lg btn--primary" href="https://biology.ucdavis.edu/news/connecting-molecular-dots-heart-disease">Read the full story to learn more about Gomes' heart disease research</a></p> </div> <div class="field field--name-field-sf-article-category field--type-entity-reference field--label-above"> <div class="field__label">Category</div> <div class="field__item"><a href="/articles/human-animal-health" hreflang="en">Human &amp; Animal Health</a></div> </div> Mon, 14 May 2018 16:30:21 +0000 David Slipher 91 at https://bmcdb.ucdavis.edu Jennifer Whistler: On the Search for Safer Opioids https://bmcdb.ucdavis.edu/news/jennifer-whistler-search-safer-opioids <span class="field field--name-title field--type-string field--label-hidden">Jennifer Whistler: On the Search for Safer Opioids</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/16" typeof="schema:Person" property="schema:name" datatype="">David Slipher</span> </span> <span class="field field--name-created field--type-created field--label-hidden">April 21, 2018</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/Jennifer-Whistler-Opioids-UC-Davis.jpg?h=06ac0d8c&amp;itok=JIVjEOp9" width="1280" height="720" alt="Jennifer Whistler" title="Whistler tests a mouse&#039;s ability to learn new rules. Mice who experience opioid withdrawal are less able to learn new rules. In this experiment, the red light mimics darkness, allowing Whistler to study the mice&#039;s behavior at night. David Slipher/UC Davis" typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="According to BMCDB Graduate Group member Jennifer Whistler, professor of Physiology and Membrane Biology, opioid drug development is headed in the wrong direction. Whistler wants to create a balanced opioid that more closely mimics the way endorphins in the body switch pain relief on and off.   "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "According to BMCDB Graduate Group member Jennifer Whistler, professor of Physiology and Membrane Biology, opioid drug development is headed in the wrong direction. Whistler wants to create a balanced opioid that more closely mimics the way endorphins in the body switch pain relief on and off.   " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The opioid epidemic has been called the “deadliest drug crisis in American history” by the <a href="https://www.nytimes.com/2017/10/26/us/opioid-crisis-public-health-emergency.html"><em>New York Times</em></a><em>. </em>Overdoses claim the lives of more than 90 Americans each day, and about two million people battle substance abuse disorders stemming from prescription opioids, according to the National Institute on Drug Abuse.</p> <p>According to BMCDB Graduate Group member Jennifer Whistler, professor of Physiology and Membrane Biology, drug development is headed in the wrong direction. Whistler wants to create a balanced opioid that more closely mimics the way endorphins in the body switch pain relief on and off.  </p> <p><a class="btn--primary" href="https://biology.ucdavis.edu/news/jennifer-whistler-search-safer-opioids">Read the full story to learn more about Whistler's opioid research</a></p> </div> <div class="field field--name-field-sf-article-category field--type-entity-reference field--label-above"> <div class="field__label">Category</div> <div class="field__item"><a href="/articles/human-animal-health" hreflang="en">Human &amp; Animal Health</a></div> </div> Sat, 21 Apr 2018 23:27:08 +0000 David Slipher 116 at https://bmcdb.ucdavis.edu Zebrafish Reproductive Development May Hold Insights into Ovarian Cancer https://bmcdb.ucdavis.edu/news/zebrafish-reproductive-development-may-hold-insights-ovarian-cancer <span class="field field--name-title field--type-string field--label-hidden">Zebrafish Reproductive Development May Hold Insights into Ovarian Cancer</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span lang="" about="/user/16" typeof="schema:Person" property="schema:name" datatype="">David Slipher</span> </span> <span class="field field--name-created field--type-created field--label-hidden">March 31, 2018</span> <div class="field field--name-field-sf-primary-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/dgvnsk4686/files/styles/sf_landscape_16x9/public/images/article/draper-and-leeberg_1500.jpg?h=c673cd1c&amp;itok=wdMriN-j" width="1280" height="720" alt="Dena Leerberg and Associate Professor Bruce Draper, Department of Molecular and Cellular Biology" title="NIH T32 predoctoral training grant recipient Dena Leerberg, &#039;17 Ph.D., and Associate Professor Bruce Draper, Department of Molecular and Cellular Biology, study reproductive development in zebrafish. David Slipher/UC Davis" typeof="foaf:Image" class="image-style-sf-landscape-16x9" /> </div> <div class="addthis_toolbox addthis_default_style addthis_32x32_style" addthis:url="https://bmcdb.ucdavis.edu/news.rss" addthis:title="News" addthis:description="BMCDB Graduate Group member Associate Professor Bruce Draper, is studying zebrafish to learn about the genetics of sexual reproduction in vertebrates. Draper’s research, published in PLOS Genetics with postdoc and Dena Leerberg, ’17 Ph.D., may advance discoveries into the origins of ovarian cancer.  "> <a class="addthis_button_facebook"></a> <a class="addthis_button_linkedin"></a> <script> var addthis_share = { templates: { twitter: "BMCDB Graduate Group member Associate Professor Bruce Draper, is studying zebrafish to learn about the genetics of sexual reproduction in vertebrates. Draper’s research, published in PLOS Genetics with postdoc and Dena Leerberg, ’17 Ph.D., may advance discoveries into the origins of ovarian cancer.  " } } </script> <a class="addthis_button_twitter"></a> <a class="addthis_button_email"></a> <a class="addthis_button_compact"></a> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>With funding from the National Institutes of Health and the National Science Foundation, BMCDB Graduate Group member Associate Professor Bruce Draper, Department of Molecular and Cellular Biology, is studying zebrafish (<em>Danio rerio</em>) to learn about the genetics of sexual reproduction in vertebrates. Draper’s research, published in <a href="http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006993#sec009"><em>PLOS Genetics</em></a> with postdoc and Dena Leerberg, ’17 Ph.D., may advance discoveries into the origins of ovarian cancer. </p> <p>Humans share some 70 percent of DNA with the fish, and 84 percent of the genes associated with human disease have counterparts in zebrafish. These genetic relationships make zebrafish a valuable tool for researchers.</p> <p>But what makes the zebrafish species a truly powerful model organism is its transparency. Zebrafish embryos are clear, providing scientists a window into the biological machinery behind the fish’s formation.</p> <p><a class="btn--primary" href="https://biology.ucdavis.edu/news/zebrafish-reproductive-development-may-hold-insights-ovarian-cancer">Read the full story to explore Draper's research on zebrafish</a></p> </div> <div class="field field--name-field-sf-article-category field--type-entity-reference field--label-above"> <div class="field__label">Category</div> <div class="field__item"><a href="/articles/human-animal-health" hreflang="en">Human &amp; Animal Health</a></div> </div> Sat, 31 Mar 2018 21:25:51 +0000 David Slipher 121 at https://bmcdb.ucdavis.edu