In order to generate energy, our bodies transfer electrons from food—sugars, fats and proteins—to molecular oxygen, which allows our cells to respire and function. Performed by the mitochondrial electron transport chain (ETC), this process creates energy-storing and -transporting adenosine triphosphate (ATP), the “molecular currency” for energy in the cell.
When nibbling mosquitoes cause irritation, the sensible move is to grab mosquito repellent. Distinguished Professor Walter Leal, Department of Molecular and Cellular Biology, likes to remind his students of this. But if they’re stepping outside for only a short period of time during the buggy Davis summers, Leal will offer a natural repellent like methyl salicylate, otherwise known as wintergreen oil.
Unlike the stem cells of an adult human, the stem cells of an adult Hydra—a small freshwater invertebrate related to jellyfish and corals—are in a constant state of renewal, bestowing it with amazing regenerative capabilities and nearly biological immortality. Around 100,000 cells make up the Hydra body, and amazingly, these cells renew every 20 days thanks to the Hydra’s bottomless well of stem cells.
The co-evolutionary arms race between plants and pathogens is one of biological balance. Plants want to defend themselves from invaders, while pathogens want to infect their hosts without killing them to propagate. Plant biologists are keen to understand the molecular battles occurring in infected plant cell territory.
For his excellence in research, Dinesh-Kumar has received the American Phytopathological Society's Noel T. Keen Award
His interest in plants goes back to his youth working with his father on his family's farm in India
His well-published research focuses on host-microbe interactions and plant defense tactics
Congratulations to Jamie Ho, current BMCDB second year student, and Yesica Mercado-Ayon, UCD PREP Scholar and incoming BMCDB student, on being selected for the 2019 NSF GRFP Fellowships!
When a healthy cell turns cancerous a cascade of events enables the cancer to spread throughout the body. But its origin lies within a single progenitor cell.
“What goes wrong with that particular cell?” asked Assistant Professor Chang-il Hwang, Department of Microbiology and Molecular Genetics. “Something happens at the molecular level. One DNA molecule, or one protein molecule changes.”
In a study appearing in Genetics, BMCDB Graduate Group faculty chair Bruce Draper and UC Davis researchers relay new discoveries about the molecular mechanisms behind sexual determination. Using zebrafish, they highlighted the gene responsible for determining whether the fish will develop into a female or a male.
In a paper appearing in Cell Metabolism, Associate Professor Mark Huising, Department of Neurobiology, Physiology and Behavior, and Biochemistry, Molecular, Cellular and Developmental Biology graduate student Sharon Lee refute a previous study that claimed an antimalarial drug could be used to treat type 1 diabetes.
Associate Professor Aldrin Gomes, Department of Neurobiology, Physiology and Behavior, studies the underpinnings of heart disease. He’s searching for molecular clues that will help medical professionals better manage heart disease.